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In June 2017, NICE updated recommendation 1.2.7 to clarify the advice on what imaging should be done.
Excerpt
Spondyloarthritis encompasses a group of inflammatory conditions with some shared features, including extra-articular manifestations. Both peripheral and axial joints can be affected. The spondyloarthritides are distinct from rheumatoid arthritis but are as important to recognise and manage early in their presentation to improve health outcomes.
The majority of people with these conditions have either psoriatic arthritis or axial spondyloarthritis, which includes ankylosing spondylitis. Ankylosing spondylitis and non-radiographic axial spondyloarthritis primarily affect the spine, in particular the sacroiliac joint. Both conditions manifest in similar ways; the primary classification difference is whether sacroiliitis is detectable on X-ray.
Psoriatic arthritis may manifest in a number of different patterns. These include predominant involvement of small joints in the hands and feet, predominant large joint involvement particularly in the knees or combinations of these. Psoriatic arthritis may also involve the axial joints, and inflammation of the entheses and/or finger and toe joints. Skin and nail involvement may not be present at diagnosis and in its absence, a family history of psoriasis is required to meet the diagnostic criteria.
Less common subgroups are enteropathic spondyloarthritis, which is associated with inflammatory bowel disease (Crohn’s disease and ulcerative colitis), and reactive arthritis, which can occur in people following gastrointestinal or genitourinary infections.
The final subgroup is people who have undifferentiated spondyloarthritis. These people generally have an asymmetrical oligoarticular (fewer than 5 involved joints) arthritis, often involving the knees. They do not meet the diagnostic criteria of the other subgroups at presentation but their disease may evolve to do so at a later stage.
This guideline also includes people who are 16 years or older with axial or peripheral symptoms who have previously been diagnosed with juvenile idiopathic arthritis.
Healthcare professionals in non-specialist settings do not always recognise the signs and symptoms of spondyloarthritis, particularly spinal symptoms, which may be mistakenly attributed to other causes of low back pain. This can lead to substantial delays in diagnosis and treatment with consequent disease progression and disability. This guideline seeks to raise awareness of the features of spondyloarthritis and provide clear advice on what action to take when people with signs and symptoms first present in healthcare settings.
This guideline also provides advice on the interventions available to people with spondyloarthritis. These include pharmacological and non-pharmacological treatments, and surgery. The guidance also provides advice on how care for people with spondyloarthritis should be organised across healthcare settings, and what information and support should be provided.
Contents
- 1. Summary section
- 2. GDG membership and ICG technical team
- 3. Strength of recommendations
- 4. Methods
- 5. List of recommendations
- 6. Recognition, referral and diagnosis
- 7. Pharmacological management
- 7.1. Pharmacological interventions for axial symptoms of spondyloarthritis
- 7.2. Pharmacological management of peripheral spondyloarthritis
- 7.3. Switching or augmenting pharmacological interventions for spondyloarthritis
- 7.4. Biological DMARDs for spondyloarthritis
- 7.5. Long-term antibiotics for reactive arthritis
- 8. Non-pharmacological management
- 9. Surgical Interventions
- 10. Organisation of care and long-term monitoring
- 10.1. Transition from paediatric to adult rheumatology services
- 10.2. Monitoring of pharmacological interventions used in spondyloarthritis
- 10.3. Care setting for management of flare episodes
- 10.4. Care setting for long-term management
- 10.5. Cross-speciality care
- 10.6. Complications of spondyloarthritis
- 10.7. Complications of treatments for spondyloarthritis
- 11. Information for people with spondyloarthritis
- 12. Glossary
- Appendices
- Appendix A. Committee membership list – Spondyloarthritis guideline Committee
- Appendix B. Guideline scope
- Appendix C. Review protocols
- Appendix D. Review search strategy
- Appendix E. Evidence tables
- Appendix F. Excluded studies
- Appendix G. GRADE tables and meta-analysis results
- Appendix H. Full health economics report
- Appendix I. Expert witness testimonial
- Appendix J. Spondyloarthritis: NMA on pain outcome: CGTSU, Bristol (Edna Keeney and Sofia Dias)
- Appendix K. Research recommendations
- Appendix L. Review flowcharts
Final version
Developed by the National Institute for Health and Care Excellence
Disclaimer: Healthcare professionals are expected to take NICE clinical guidelines fully into account when exercising their clinical judgement. However, the guidance does not override the responsibility of healthcare professionals to make decisions appropriate to the circumstances of each patient, in consultation with the patient and/or their guardian or carer.
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- Spondyloarthritis in over 16s: diagnosis and managementSpondyloarthritis in over 16s: diagnosis and management
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